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Introducción: El dengue es una enfermedad de interés para la salud pública por el difícil control, la expansión acelerada en países tropicales y subtropicales, la inexistencia de vacunas o medicamentos específicos y la desatención de comunidades con altos niveles de vulnerabilidad y riesgos de enfermar o morir. Objetivo: Explorar las prácticas ancestrales en el control del dengue utilizadas por indígenas de una comunidad embera katío en Córdoba, Colombia. Métodos: Estudio cualitativo con diseño microetnográfico, desarrollado con 20 miembros de una de las comunidades indígenas embera katío del Departamento de Córdoba, Colombia, entre junio de 2019 y mayo de 2020. La recolección de datos se hizo mediante una entrevista a profundidad, desde los postulados de Leininger. Los hallazgos se organizaron, sistematizaron e interpretaron bajo la técnica de análisis de contenido. Resultados: Se pudo constatar que, en la comunidad sujeto de estudio, persiste el uso de prácticas ancestrales, dentro de las cuales se destaca la utilización de plantas en forma de baños y bebidas. Asimismo, el control de las enfermedades se vincula con costumbres basadas en rituales, cantos y procedimientos realizados por el Jaibaná, donde se integra la conexión entre el mundo espiritual, cultural y corporal. Conclusiones: Las plantas de mayor uso para el control del dengue son balsamina (Momordica charantia), corrata (Simaba cedron Planch.), gavilán (Simarouba glauca DC.), matarratón (Gliricidia sepium) y limoncillo (Cymbopogon citratus). Se requiere implementar miradas transdisciplinares y transculturales que potencien la capacidad de las familias como cuidadoras primarias, y de enfermería como agente en la identificación precoz de necesidades e implementación de planes de cuidado(AU)
Introduction: Dengue is a disease of public health concern, due to its difficult control, accelerated expansion in tropical and subtropical countries, the nonexistence of vaccines or specific drugs, as well as the neglect of communities with high levels of vulnerability and morbidity and mortality risks. Objective: To explore the ancestral practices of dengue control used by indigenous people from the Embera Katío community in Córdoba, Colombia. Methods: Qualitative study, with a microethnographic design, developed with twenty members from Embera Katío, one of the indigenous communities in the Córdoba Department, Colombia, between June 2019 and May 2020. Data collection was carried out through in-depth interview, following Leininger postulates. The findings were organized, systematized and interpreted using the content analysis technique. Results: It was found that, in the community under study, the use of ancestral practices persists, among which the use of herbs in the form of baths and drinks stands out. Likewise, disease control is linked to customs based on rituals, chants and procedures performed by the Jaibaná, integrating the spiritual, cultural and corporeal worlds. Conclusions: The most commonly used herbs for dengue control are balsam-pear (Momordica charantia), cedron (Simaba cedron [Planch.]), paradise tree (Simarouba glauca [DC.]), quickstick (Gliricidia sepium) and lemongrass (Cymbopogon citratus). It is necessary to implement transdisciplinary and transcultural approaches, in order to enhance the capacity of families as primary caregivers, as well as of nurses as agents in the early identification of needs and the implementation of care plans(AU)
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Humans , Residence Characteristics , Indigenous Peoples , Data CollectionABSTRACT
Objective:To explore the effect of spironolactone combining Chinese medical herbs on the treatment of patients with diabetic nephropathy. Methods:Diabetes patients with stage III diabetic nephropathy were randomized into 2 group (24 cases in each group) . A group was treated with spironolactone, while B group were treated with spironolactone combining Chinese medical herbs both for 2 months. Urinary albumin excretion rate (UAER) and creatinine (Scr) were tested on ex-treatment,at the end of treatment,and the thirth,sixth,12th month after treatment. Results:UAER and Scr of A,B group at the end of treatment,the thirth month after treatment were lower significantly than ex-treatment. UAER and Scr in B group on the point in time the sixth,12th month after treatment were lower significantly than ex-treatment. At the end of treatment, and thirth, sixth, 12th month after treatment, UAER and Scr in B group were lower than those in A group. Conclusion:The long-range effect of spironolactone combining Chinese medical herbs are better than single spironolactone on the patients with stageШdiabetic nephropathy.
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Objective]Summarize professor Wang Canhui′s experiences in chronic atrophic gastritis. [Methods] Summarize professor Wang Canhui′s experiences in chronic atrophic gastritis from etiology and pathogenesis, differential treatment, administered medical herbs and prescription and case. [Results]Professor Wang Canhui considers that chronic atrophic gastritis′ pathogenesis is deficiency of spleen and stomach, qi stagnation ,stomach heat and stagnation of stomach channel, the therapeutic methods of chronic atrophic gastritis is invigorating the spleen and reinforcing stomach, regulating vital energy, reducing fever and activating blood and dredging collaterals, the prescription is Jian Pi Yi Wei Decoction. The modified treatment based on clinical manifestation and the case in this article has obtained good treatment results. [Conclusion] Professor Wang Canhui′s academic thoughts and clinical experiences in chronic atrophic gastritis provide therapy ideas and high practical values in chronic atrophic gastritis.
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Objective To observe the therapeutic efficacy of the Chinese medical herb decoction qu yin tang combined with narrow-band ultraviolet B (NB-UVB) phototherapy on psoriasis vulgaris, and to investigate its influ-ence on osteopontin (OPN) and vascular endothelial growth factor (VEGF) in serum. Methods Sixty patients with psoriasis were randomly divided into a treatment group and a control group. The treatment group was treated with qu yin tang and NB-UVB; the control group was treated with qu yin tang only. The levels of OPN and VEGF in serum were detected in both groups before and after treatment using an enzyme-linked immunosorbent assay (ELISA). Twenty healthy persons' serum samples were taken as controls. At the same time, any changes in psoriasis area and severity index (PASI) scores in the two groups were recorded and compared. Results After 8 weeks of treatment, PASI scores and levels of OPN and VEGF had been reduced significantly in both groups, and there was a significant difference between the treatment group and the control group. Conclusions Chinese medical herbs combined with NB-UVB phototherapy is a safe and effective method for the treatment of psoriasis. The results suggested that OPN and VEGF may play an important role in the pathogenesis of psoirasis vulgaris.
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According to the experience of teaching the science of Chinese Medical Herbs Preparation,the author gives some advice such as choosing typical drugs,providing examples and setting up comprehensive and contriving experiments etc,which is worth referring to in teaching es-pecially for those who have less time in experiments.
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Objective To investigate the therapeutic effects of traditional Chinese medicinal herbs(TCMH) on benign prostate hyperplasia(BPH) and their influence on proliferation and apoptosis of prostate cells in experimental mice. Methods A total of 120 male Kunming mice(weight,30 to 40 g)were randomly divided into 5 groups:①normal control group;②hyperplastic group;③normal saline(NS)(negative control)group;④TCMH group;⑤finasteride (positive control) group.Each group included 24 mice.The mice in normal control group were killed and their prostates were weighed.The BPH model was induced by implanting the urogenital sinus in the mice in other 4 groups.In the 61st day,the prostate weight of the mice in hyperplastic group was examined after they were killed;and the mice in the remaining groups were fed with NS,TCMH and finasteride,respectively.In the 91st day,the mice in these 3 groups were killed and their prostates were weighed.The proliferation and apoptosis of the prostate cells of mice in the 3 groups were determined by flow cytometry(FCM). Results The prostates in hyperplastic group [(149.30?8.46)mg] were heavier than those in TCMH group [(85.60?17.97)mg] ( P 0.05). Conclusions The TCMH has a significant therapeutic effects on experimental mice with BPH.The mechanisms may be as follows:TCMH can regulate the relevant genes of the prostate cells so that they can promote the apoptosis of the prostate cells and as a result,the volume and weight of the prostate of the mice are reduced.
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The main reasons to doubt the validity of serum pharmacology include:①The components of medical herbs absorbed from gastrointetinal tract enter circulating plasma,not serum in vivo.②Blood coagulation involves the activation of a series of proenzymes,and the proteases induce leukocytes to release lysosomal enzymes.These enzymes may degrade some herbal components.③Thrombin can stimulate platelets and leukocytes to secrete many biologically active substances.④Fibrinolysis,complement and kinin systems are activated during blood coagulation.⑤The processes of serum preparation and inactivation always cause lose of lots of herbal components. Recently finger printing analysis using HPLC-MS and antileukemic proliferation experiments showed that the results obtained from serum pharmacological method might be incorrect. We propose that the ex vivo experiments on multiple levels are necessary to elucidate the pharmacological actions and their mechanisms of medical herbs and believe that the pharmacological method using plasma absorbed herbal components should be better than that using serum.